Development of graphene-chitosan composite modified screen-printed carbon electrode and its application for detection of rutin

5th International Seminar on Sciences

自然科学（总论）

Wahyuni, W.T.^1^2 ; Arif, Z.^1 ; Maryam, N.S.^1

Department of Chemistry, IPB University, Bogor

16680, Indonesia^1

Tropical Biopharmaca Research Center, IPB University, Indonesia^2

关键词: Analytical performance;    Chitosan composites;    Concentration ranges;    Electrochemical performance;    Limit of detection;    Limit of quantitations;    Microwave-assisted methods;    Screen-printed carbon electrodes;   

Others  :  https://iopscience.iop.org/article/10.1088/1755-1315/299/1/012005/pdf
DOI  :  10.1088/1755-1315/299/1/012005

学科分类：自然科学（综合）

来源: IOP

【 摘 要 】

Graphene is a prospective material for sensing devices due to its excellent electronic, thermal, and mechanical properties. In this study, low oxygen graphene was synthesized from graphite and nitronium ion using a microwave-assisted method. Graphene was dispersed into 0.05% chitosan solution and deposited by drop casting method on to screen-printed carbon electrode (SPCE) to form graphene-chitosan composite modified SPCE (SPCE-G-chit). The electrochemical performance of SPCE-G-chit was evaluated using flavonoid 3',4',5,7-tetrahydroxyflavone-3β-D-rutinoside (rutin). SPCE-G-chit provides linearity with R2 of 0.9944 for rutin measurement in the concentration range of 5× 10-7 to 1× 10-5 M. Meanwhile, the linearity of rutin at SPCE was lower (R2 0.9396). Limit of detection (LOD) and limit of quantitation (LOQ) of rutin measurement at SPCE-G-chit was lower (0.23 M and 0.58 M, respectively) compare to SPCE (LOD = 0.69 M and LOQ = 1.75 M, consecutively). The accuracy of rutin measurement at SPCE-G-chit was 99.45% while the accuracy of rutin measurement at SPCE was 72.18%. The result indicated that SPCE-G-chit provides superior analytical performance than SPCE and potential for electrochemical sensor development.