Antibacterial Activity of Rhinacanthus nasutus L. Kurz ointment to Inhibit Staphylococcus aureus Growth Using In Vitro Dilution Method

International Conference on Life Sciences and Technology

Lukiati, Betty^1 ; Nugrahaningsih^1 ; Prabaningtyas, Sitoresmi^1 ; Aribah, Dina^2 ; Nur Arifah, Siti^3

Department of Biology, Faculty of Mathematics and Natural Sciences, Universitas Negeri Malang, Jl. Semarang No. 5, Malang

65145, Indonesia^1

Postgraduate Program of Microbiology, Bogor Agricultural University, Bogor, Indonesia^2

Postgraduate of Biology Program, Department of Biology, Faculty of Mathematics and Natural Sciences, Universitas Negeri Malang, Jl. Semarang No. 5, Malang

65145, Indonesia^3

关键词: Anti-bacterial activity;    Antibiotic resistance;    Rhinacanthus nasutus;    Skin disease;    Staphylococcus aureus;   

Others  :  https://iopscience.iop.org/article/10.1088/1755-1315/276/1/012023/pdf
DOI  :  10.1088/1755-1315/276/1/012023

来源: IOP

【 摘 要 】

This study aimed at examining the antibacterial activity of R. nasutus ointment in different concentration of S. aureus bacteria growth by in vitro dilution method. The antibacterial activity of R. nasutus ointment was determined based on minimum inhibitory concentration (MIC) value and minimum bactericidal concentration (MBC) from R. nasutus ointment against S. aureus bacteria. The results showed R. nasutus ointment that the MIC value was 250,000 μg/mL up, whereas the MBC was 125,000 μg/mL. The variation of R. nasutus ointment concentration significantly has a relation with S. aureus bacterial growth. These results indicated that R. nasutus ointment potentially used as an alternative medicine for skin disease because it has an ability as antibacterial.