Quantitative Analysis of Sibutramine in Diet drugs by High Performance Liquid Chromatography and Evaluation of the Risk of Sibutramine in Diet drugs by BP Neural Network

2018 4th International Conference on Environmental Science and Material Application

生态环境科学;材料科学

Du, Boya^1 ; He, Xinrui^1 ; Wang, Bing^2 ; Xiao, Ruihan^2

School of Goverment, Beijing Normal University, Beijing, China^1

School of Chemistry, Beijing Normal University, Beijing, China^2

关键词: BP neural networks;    Designed experiments;    High-accuracy;    Illegal drugs;   

Others  :  https://iopscience.iop.org/article/10.1088/1755-1315/252/4/042031/pdf
DOI  :  10.1088/1755-1315/252/4/042031

来源: IOP

【 摘 要 】

Purpose to quantitatively analyse harm of 6 diet drugs containing sibutramine. Method Firstly, we used high performance liquid chromatography to determine the content of sibutramine in six diet drugs and designed experiment to obtain datas after injection of different drug samples in rats. Next, we used these datas for BP neural network training and obtained the harm values of the samples at different doses and times to human. Result The model has been tested with high accuracy. Conclusion People should stay away from illegal drugs to scientifically lose weight.