A Review of the Delivery System of Coenzyme-Q10 Based on Nanotechnology

4th International Conference on Energy Equipment Science and Engineering

Zhang, Yiyun^1

China Medical University, Liaoning province

110001, China^1

关键词: Antioxidant components;    Basic matrices;    Coenzyme Q10;    Delivery systems;    Electron carrier;    Human cells;    Nano-carriers;    Transport carriers;   

Others  :  https://iopscience.iop.org/article/10.1088/1755-1315/242/4/042003/pdf
DOI  :  10.1088/1755-1315/242/4/042003

来源: IOP

【 摘 要 】

Coenzyme-Q10 is an important electron carrier and antioxidant component participate in respiration process and universally present in human cells. A lot of researches indicated that the deficiency of coenzyme-Q10 may associated with many diseases in various organ. Although coenzyme-Q10 has been proved to be endogenous, its supply as food or drug can also alleviate or cure those diseases. For decades, researchers are trying to improve the method of coenzyme-Q10 intake facing the difficult brought by its low bioavailability as its lipophilic and unstable nature. Fortunately, recently introduced transport carriers prepared by nanotechnology with lipid as basic matrix have drawn increasingly attention. This paper summarized and classified several nano-carriers from recent reports, introducing their advantages, disadvantages and application in medicine.