The effect of Indonesian herbal drink "Mbah Jayus" on hyperglycemic rats

International Conference on Green Agro-industry and Bioeconomy

农业科学;工业技术（总论）;经济学

Widyaningsih, T.D.^1 ; Fanani, R.^2 ; Siska, A.I.^2 ; Martati, E.^1

Department of Agricultural Product Technology, Universitas Brawijaya, Malang, Indonesia^1

Graduate Stud. of Agricultural Product Technology, Universitas Brawijaya, Malang, Indonesia^2

关键词: 2 ,2-diphenyl-1-picrylhydrazyl;    Antidiabetic effects;    Antioxidant properties;    Blood glucose level;    Intraperitonial injection;    Total flavonoid contents;    Total phenolic content;    Zingiber officinale;   

Others  :  https://iopscience.iop.org/article/10.1088/1755-1315/230/1/012094/pdf
DOI  :  10.1088/1755-1315/230/1/012094

来源: IOP

【 摘 要 】

Diabetes mellitus is a metabolic disorder disease caused by disorder of insulin secretion insulin action or both. Unlike the synthetic compounds, herbal of natural origin are safer and have less side effects. One of Indonesian herbal drink called "jamu" have many health effects, one of them is antidiabetic. Indonesian herbal drink "Mbah Jayus" is made by Zingiber officinale Rosc, Cymbopogun citrate, Nigella sativa, Cinnamomum chinense BL, and Amomum cardamomum Willd which has highly antioxidant. In this study, antioxidant property was evaluated using 2,2-diphenyl-1-picrylhydrazyl radical (DPPH) scavenging method (IC50), total phenolic content and total flavonoid content. The antidiabetic effect was conducted on Rattus norvegicus rats. Diabetes was induced with intraperitonial injection of alloxan monohydrate (150 mg/kg body weight). The result showed that Indonesian herbal drink "Mbah Jayus"can decrease significantly the blood glucose level (P