Antimicrobial Activity of Ethanol Extract of Abrus precatorius L. Roots against Planktonic Cells and Biofilm of Urine and Blood Methicillin Sensitive Staphylococcus aureus (MSSA) Isolate

12th Congress of Indonesian Soc. for Biochemistry and Molecular Biology in Conjunction With The 2nd Int. Conf. "Collaboration Seminar of Chemistry and Industry

生物科学;化学

Mutmainnah, B.^1 ; Ni'Matuzahroh^2^3 ; Baktir, A.^4

Faculty of Science and Technology, University Airlangga, Jl. Mulyorejo, Jawa Timur

60511, Indonesia^1

Academy of Dental Health Karya Adi Husada Mataram, Soedjono Lingkar Selatan, Mataram

83611, Indonesia^2

Department of Biology, Faculty of Science and Technology, University Airlangga, Jl. Mulyorejo, Surabaya, Jawa Timur

60511, Indonesia^3

Department of Chemistry, Faculty of Science and Technology, University Airlangga, Jl. Mulyorejo, Surabaya

60115, Indonesia^4

关键词: Anti-microbial activity;    Bacterial biofilm;    Biofilm formation;    Inhibitory effect;    Methicillin-sensitive staphylococcus aureus;    Microtiter plates;    Planktonic bacteria;    Staphylococcus aureus;   

Others  :  https://iopscience.iop.org/article/10.1088/1755-1315/217/1/012027/pdf
DOI  :  10.1088/1755-1315/217/1/012027

学科分类：生物科学（综合）

来源: IOP

【 摘 要 】

The purpose of this study was to to compare the antibiofim activity of ethanol extract of Abrus precatorius L. roots at various concentrations of the Indonesian isolate of Staphylococcus aureus biofilm. The method used included inhibition test of planktonic bacteria and inhibition test of bacterial biofilm. The variable measured is the optical density (OD) of biofilm formation tested by ELISA reader. Inhibition test of biofilm formation is carried out using the microtiter plate method. The results showed that ethanol extract of A. precatorius L. roots had a significant differences in the inhibitory effect on biofilm formation between treatment group and positive control. The linear regression test showed that antibiofilm activity of ethanol extract of A. precatorius L. roots was slightly stronger on blood MSSA isolate. Therefore, the ethanol extract of A. precatorius L. roots have antibiofilm activity for MSSA isolate.