In vitro of Mg-1.6 Gd alloys after hot extruded for biomaterial application

Conference on Innovation in Technology and Engineering Science

工业技术（总论）

Susanti, O.^1 ; Bachtiar, E.W.^2 ; Harjanto, S.^3 ; Gunawarman^1

Metalurgy Laboratory, Mechanical Engineering Department, Universitas Andalas, Padang, Indonesia^1

Department and Laboratory of Oral Biology, Faculty of Dentistry, Universitas Indonesia, Jakarta, Indonesia^2

Department of Metallurgical and Materials Engineering, Faculty of Engineering Universitas Indonesia, Kampus UI Depok

16424, Indonesia^3

关键词: Biodegradable implants;    Biomaterial application;    Cell viability;    Hot-rolled;    In-vitro;    Osteoblast cells;    Thermomechanical process;    Toxic effect;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/602/1/012091/pdf
DOI  :  10.1088/1757-899X/602/1/012091

学科分类：工业工程学

来源: IOP

【 摘 要 】

Mg-1.6Gd (wt%) alloys have attracted interest in biodegradable implant materials because of the potential to eliminate secondary surgeries. The purpose of this study was to evaluate the in vitro degradation performance of the alloys after the thermo-mechanical process (hot extruded and hot rolled) and to determine whether the materials are sustainable for further investigation. The performances of the Mg-1.6Gd alloys was using cell viability (MTT) test during the experiment. The results showed that verified viable the osteoblast cell on all the different thermo-mechanical process and no obvious toxic effect within the various time.