Study on the Biocompatibility of Mg-4.0Zn-1.0Sr-0.4Ca Alloy with Phosphating Treatment after Implantation in Rats

5th Annual International Workshop on Materials Science and Engineering

Cui, Tong^1 ; Liu, Yan^1 ; Chen, Suiyuan^1 ; Qin, Haiming^2 ; Song, Fulin^2

College of Materials Science and Engineering, Northeastern University, Shenyang

110004, China^1

Department of Pathology, Northern Hospital, Shenyang

110016, China^2

关键词: Alloy surfaces;    Bone tissue;    Brain tissue;    Calcium hydrogen phosphate;    Kidney tissues;    Leg muscles;    Liver tissue;    Myocardial tissue;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/585/1/012056/pdf
DOI  :  10.1088/1757-899X/585/1/012056

来源: IOP

【 摘 要 】

The phosphating treatment coating is prepared on Mg-4.0Zn-1.0Sr-0.4Ca alloy surface, and the phosphating coating is consisted with HA and a small amount of calcium hydrogen phosphate hydrate. The hemolysis rate of both phosphated coating and uncoated samples is less than 5 %, showing that both have good hemolytic resistance which meet the requirements of use. It is found through the pathological studies that after implantation Mg-4.0Zn-1.0Sr-0.4Ca alloy for 30 days, for the leg muscle tissue, kidney tissue, liver tissue and bone tissues of rat the inflammation phenomenon is gradually recovered or completely recovered being passed the corrosion peak, while for the rat implanted the phosphating treatment alloy was in the acute stage of inflammation. After implantation Mg-4.0Zn-1.0Sr-0.4Ca alloy and the phosphating treatment alloy for 30 days, all of the brain tissue, myocardial tissue, lung tissue, intestinal tissue are unaffected.