Synthesis and characterization of chitosan:SiO2 nanocomposite by ultrasonic spray drying

1st Siliwangi International Conference on Innovation in Research 2018

Azhary, S.Y.^1 ; Purnama, D.^2 ; Florena, F.F.^3 ; Vanitha, M.^4 ; Muchtaridi^2 ; Panatarani, C.^4^5 ; Joni, I.M.^4^5

Dept. of Environmental Science, Graduate School, Universitas Padjadjaran, Jl. Raya Bandung-Sumedang Km 21, Jatinangor, Jawa Barat

45363, Indonesia^1

Dept. of Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Jl. Raya Bandung-Sumedang Km 21, Jatinangor, Jawa Barat

45363, Indonesia^2

Dept. of Physics, Graduate School, Institute of Technology Bandung, Jl. Ganesha No.10, Kota Bandung, Jawa Barat

40132, Indonesia^3

Dept. of Physics, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Jl. Raya Bandung-Sumedang Km 21, Jatinangor, Jawa Barat

45363, Indonesia^4

Nanotechnology and Graphene Research Center, Universitas Padjadjaran, Jl. Raya Bandung-Sumedang, Jatinangor, Jawa Barat

45363, Indonesia^5

关键词: Chemical bondings;    Chitosan particles;    Composite particles;    Drug delivery system;    FT-IR investigation;    Narrow size distributions;    Spherical morphologies;    Synthesis and characterizations;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/550/1/012037/pdf
DOI  :  10.1088/1757-899X/550/1/012037

来源: IOP

【 摘 要 】

Chitosan:SiO2 nanocomposite (Cs:SiO2 NCs) is synthesized via aerosol processing. Ultrasonic spray drying apparatus was used to produce smaller sized composite particles with spherical morphology. Composite from shrimp shell and water glass (Na2SiO3) as silica precursor were used for the preparation. Cs:SiO2 NCs were characterized by Fourier Transform Infrared (FTIR) spectroscopy and scanning electron microscopy (SEM) to know about the chemical bonding and morphology of the particles, respectively. Based on the FTIR investigation the absorption peak at 1090 cm-1 represents the reaction of silanol groups of silica with carbonyl groups of polymers leading to the formation of Si-O-C bonds. The morphology of Cs:SiO2 NCs was more spherical than chitosan particles with relatively narrow size distribution. The smaller particle size of Cs:SiO2 NCs is potentially applied to engineer the material for drug delivery system.