Automated chemiluminescent analysis of the antioxidant and prooxidant activity of natural and synthetic substrates having perspective for bioengineering

International Workshop "Advanced Technologies in Material Science, Mechanical and Automation Engineering – MIP: Engineering – 2019"

材料科学;机械制造;原子能学

Lesovskaya, M.I.^1 ; Shaporova, Z.E.^1 ; Pyzhikova, N.I.^1

Krasnoyarsk State Agrarian University, Ministry of Agriculture of Russia, 90, Mira ave., Krasnoyarsk, Russia^1

关键词: Antioxidant capacity;    Chemiluminescent analysis;    Dynamic development;    Experimental modeling;    Extraction conditions;    Pro-oxidant properties;    Prooxidant compounds;    Synthetic substrates;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/537/6/062008/pdf
DOI  :  10.1088/1757-899X/537/6/062008

学科分类：材料科学（综合）

来源: IOP

【 摘 要 】

Automated CL-control has a lot of advantages, such as rapidity, information value, objectivity, reproducibility, low-price. As a rule, the method is used for detecting antioxidant capacity of natural substrates. The results described in the paper show that this method has wide opportunities for deciding actual tasks in nutritional industry, preventive and restorative medicine, bioengineering in future. First, the results demonstrated that the method allows to determine optimal extraction conditions to obtain phytopreparates which include nonstability antioxidant and (or) prooxidant compounds. This is shown using phytopreparates (leuzea, rhodiola, rheum, plantago) obtained using local plant materials. Second, results are obtained to determine the presence of real, non-virtual antioxidant or prooxidant properties of commercial micronutrients complexes. In addition, the method allows to provide an individual selection of nutrients in accordance with the characteristics of the ROS balance of the internal environment of the consumer's body. This way allows to get the reproducible results within a relevant experimental model in short time, which is very important looking for dynamic development of the functional nutrients market. Finally, using this method one get more effective and economic navigation of chemical synthesis. As a result, the efficiency of the subsequent functionalization of synthetic compounds is increased.