Study of the effect of the introduction of heparin on the mechanical properties of polylactide

Fourth interdisciplinary scientific forum with international participation "New materials and promising technologies"

Sevostyanov, M.A.^1 ; Baikin, A.S.^1 ; Nasakina, E.O.^1 ; Sergienko, K.V.^1 ; Kaplan, M.A.^1 ; Leonov, A.V.^1 ; Kolmakova, A.A.^1 ; Danilova, E.A.^1 ; Shatova, L.A.^2 ; Leonova, N.P.^1 ; Kolmakov, A.G.^1

A.A. Baikov Institute of Metallurgy and Materials Science, Russian Academy of Sciences, Moscow, Russia^1

Voronezh State Technical University, st. 20-letiya Oktyabrya 84/4, Voronezh, Russia^2

关键词: Biodegradable film;    Poly lactide;    Polymeric composites;    Thickness of the film;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/525/1/012098/pdf
DOI  :  10.1088/1757-899X/525/1/012098

来源: IOP

【 摘 要 】

The paper describes a method for the preparation of polymeric composite films for medical purposes based on polylactide with introduced heparin. The effect of the molecular weight of polylactide and the concentration of the drug on the mechanical properties and thickness of the films obtained was studied. The possibility of creating biodegradable films with the introduced drug with given properties is shown.