Biocatalytic transformation of various mycotoxins: modern problems and existing potential

Fourth interdisciplinary scientific forum with international participation "New materials and promising technologies"

Ahundov, R.^1 ; Lyagin, I.^1^2 ; Senko, O.^1^2 ; Maslova, O.^1 ; Makhlis, T.^1 ; Efremenko, E.^1^2

Lomonosov Moscow State University, Moscow, Russia^1

Emanuel Institute of Biochemical Physics RAS, Moscow, Russia^2

关键词: Biochemical mechanisms;    Decontamination activity;    Effective materials;    Genes encoding;    Laccases;    Micotoxins;    Products of reaction;    Toxic effect;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/525/1/012090/pdf
DOI  :  10.1088/1757-899X/525/1/012090

来源: IOP

【 摘 要 】

A number of microorganisms and some plants have biochemical mechanisms of protection against the toxic effects of mycotoxins. The transformation of mycotoxins in the cells of these organisms is catalyzed by a number of enzymes, including oxidases, peroxidases, lactone hydrolases, laccases, lipases, amidases, aminotransferases, etc. recombinant variants of enzymes obtained by cloning the genes encoding these enzymes. The enzymes are basis for the development of new effective materials with decontamination activity against different micotoxins. The investigation and knowledge about the properties of the enzymes, sources of their isolation and specificity of their action as well as products of reactions catalyzed by them compose the modern scientific base for creation of new effective protective means (sorbents, fabrics etc.).