Antibacterial cream formulation of ethanolic Pliek U extracts and ethanolic residue hexane Pliek U extracts against Staphylococcus aureus

8th Annual International Conference 2018 on Science and Engineering

工业技术（总论）

Rahmad, R.^1 ; Earlia, N.^2 ; Nabila, C.^3 ; Inayati, I.^3 ; Amin, M.^4 ; Prakoeswa, C.R.S.^5 ; Khairan, K.^2 ; Idroes, R.^2^3

Department of Chemistry, Faculty Mathematics and Natural Sciences, Universitas Syiah Kuala, Banda Aceh

23111, Indonesia^1

Graduate School of Mathematics and Applied Sciences, Universitas Syiah Kuala, Banda Aceh

23111, Indonesia^2

Department of Pharmacy, Faculty Mathematics and Natural Sciences, Universitas Syiah Kuala, Banda Aceh

23111, Indonesia^3

Department of Biology, Faculty of Mathematics and Natural Science, Universitas Negeri Malang, Malang

65145, Indonesia^4

Department of Dermatology and Venereology, Faculty of Medicine, Universitas Airlangga, Surabaya

60132, Indonesia^5

关键词: Anti-bacterial activity;    Anti-microbial properties;    Free fatty acid;    Inhibition zones;    Lauric acid;    Staphylococcus aureus;    Traditional food;    Traditional medicinal plants;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/523/1/012011/pdf
DOI  :  10.1088/1757-899X/523/1/012011

学科分类：工业工程学

来源: IOP

【 摘 要 】

Indonesia as the largest archipelago country in the world is also known as a country with plenty of natural resources that can be used as traditional medicinal plants. Pliek U is a fermented crude coconut meat has been used as an ingredient in Aceh traditional food and also used as a traditional topical medicine in Aceh. Pliek U is potential as a source of free fatty acids (FFAs) such as lauric acid and monolauric acid which have antimicrobial properties. The aim of this study is to determine the activity ethanolic Pliek U extracts (EPUE) and ethanolic of residue hexane of Pliek U extracts (ERHPUE) and also the activities of their cream formulation against Staphylococcus aureus The antibacterial activity was determined by disc difussion method with clindamycin as a positive control. The antibacterial activity results showed that EPUE has antibacterial activity against Staphylococcus aureus with diameter inhibition zone of 8.66 0.57 mm, while ERHPUE and their cream have no activity against Staphylococcus aureus.