Synthesis, morphological, optical properties of functionalized La0.33Ca0.67MnO3 for antibacterial therapy

13th Joint Conference on Chemistry

Edobor-Osoh, Abiola^1^3 ; Ita, Benedict Iserom^1^2 ; Ajanaku, Kolawole Oluseyi^1 ; De La Presa, P.^3 ; Ehi-Eromosele, Cyril O.^1 ; Olorunsola, S.J.^4 ; Owolabi, F.E.^1

Department of Chemistry, Covenant University, Ota, Ogun State, Nigeria^1

Department of Pure and Applied Chemistry, University of Calabar, Cross River State, Nigeria^2

Applied Magnetism Institute, UCM-ADIF-CSIC, Las Rozas

28230, Spain^3

Department of Biological Sciences, Covenant University, Ota, Ogun State, Nigeria^4

关键词: Anti-microbial properties;    Biologically active ligands;    Citrate ligands;    Functionalizations;    Morphological properties;    Pseudomonas aeruginosa;    Staphylococcus aureus;    UV-visible spectrophotometer;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/509/1/012040/pdf
DOI  :  10.1088/1757-899X/509/1/012040

来源: IOP

【 摘 要 】

A functionalized paramagnetic manganite La0.33Ca0.67MnO3 was investigated for its morphological, optical and antimicrobial properties. The manganite was capped by using a citrate ligand. The UV-visible spectrophotometer was used in monitoring the optical bands of the metal-citrate complex. It was observed to absorb in the visible region. The metal-citrate was reacted with a biologically active ligand (N-(3-nitrophenyl)-3-phenyl-2-(phenylsulfonamido) propanamide). The optical bands observed from the metal-citrate were used in monitoring the reaction between the metal-citrate and N-(3-nitrophenyl)-3-phenyl-2-(phenylsulfonamido) propanamide). The morphological property of the product formed was determined using SEMEDAX. The effect of the complex formed on the organic ligand, N-(3-nitrophenyl)-3-phenyl-2-(phenylsulfonamido) propanamide) was determined using 1H and 13C NMR. The bacterial inhibitory property of the metal-citrate-N-(3-nitrophenyl)-3-phenyl-2-(phenylsulfonamido) propanamide) complex was determined against Pseudomonas aeruginosa and Staphylococcus auerus. It was observed to inhibit the growth of Staphylococcus aureus only. The biological activities of the metal-citrate N-(3-nitrophenyl)-3-phenyl-2-(phenylsulfonamido) propanamide) suggest its use as an alternative antibacterial therapy.