Preparation and application of dialdehyde pullulan for the construction of gelatin hydrogels

2nd International Workshop on Materials Science and Mechanical Engineering

机械制造;材料科学

Zhang, L.R.^1 ; Zhang, A.L.^1 ; Zhang, H.Z.^1 ; Liu, J.^1 ; Tang, K.Y.^1

College of Materials Science and Engineering, Zhengzhou University, Zhengzhou

450001, China^1

关键词: Aqueous phase;    Cross linking agents;    Gelatin hydrogels;    Oxidation degree;    Pullulans;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/504/1/012029/pdf
DOI  :  10.1088/1757-899X/504/1/012029

学科分类：材料科学（综合）

来源: IOP

【 摘 要 】

In this work, dialdehyde pullulans with different aldehyde contents were successfully prepared with periodate oxidizationmethod and used as cross-linking agent for the construction of gelatin hydrogels. It was found that aldehyde contents can be varied by changing pH of the aqueous phase. The highest oxidation degree as well as the content of dialdehyde groups was found at pH 4.0. The mechanical properties of the gelat in hydrogels were significantly improved with the addition of dialdehyde pullulan. The fascinating reinforcing performance of the dialdehyde pullulan extends the potential application of hydrogels in the biomedical area.