A Compact High Field Magnet System for Medical Applications

27th International Cryogenics Engineering Conference and International Cryogenic Materials Conference 2018

Hills, M.J.^1 ; Amirkhanlou, S.^3 ; Bayliss, V.^1 ; Bradshaw, T.W.^1 ; Crook, M.R.^1 ; Damiani, G.^1 ; Durrell, J.H.^2 ; Greenwood, S.^1 ; Grovenor, C.R.M.^3 ; Matthews, G.^3 ; Speller, S.C.^3 ; Zhou, D.^2

STFC, Rutherford Appleton Laboratory, Chilton, Didcot

OXON OX11 0QX, United Kingdom^1

Cambridge University, Engineering Department, Trumpington Street, Cambridge

CB2 1PZ, United Kingdom^2

Department of Materials, University of Oxford, Parks Road, Oxford

OX1 3PH, United Kingdom^3

关键词: Area of interest;    Attractive solutions;    Bulk superconductors;    High field magnets;    High magnetic fields;    Magnetic cell separations;    Magnetic nano-particles;    State of the art;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/502/1/012164/pdf
DOI  :  10.1088/1757-899X/502/1/012164

来源: IOP

【 摘 要 】

High magnetic field gradients can be used for various medical applications including magnetically targeted drug delivery, magnetic cell separation and controlled local heating for the ablation of tumours. These processes involve the use of biocompatible magnetic nanoparticles directed to the area of interest by the use of a field gradient. The force on the nanoparticle is proportional to the field gradient product, so high fields are required for effective delivery. Bulk superconductors are an attractive solution for both drug delivery and the next generation of low cost magnetic resonance imaging magnets. In particular, MgB2 is seen as an attractive material due to its low cost, simple processing and relatively high transition temperature (∼39 K). This paper describes the development of a breadboard compact delivery system suitable for medical applications. This incorporates a cryogenic stage which utilises long life space-proven technology and state of the art ex-situ processed MgB2 pellets.