The effects of electromagnetic field and γ-radiation on cell proliferation and regeneration in planarian Schmidtea mediterranea

2nd International (15th Regional) Scientific Conference "Technogenic Systems and Environmental Risk"

工业技术（总论）;生态环境科学

Sarapultseva, E.I.^1^2^3 ; Matchuk, O.N.^2 ; Uskalova, D.^1 ; Markina, H.^1 ; Savina, N.^1 ; Zamulaeva, I.A.^1^2

Institute of Nuclear Power Engineering NRNU MEPhI, Obninsk, Russia^1

A. Tsyb Medical Radiological Research Center, National Medical Research Radiological Center, Ministry of Health of the Russian Federation, Obninsk, Russia^2

National Research Nuclear University MEPhI, Moscow, Russia^3

关键词: 900 MHz;    Experimental evidence;    Gamma irradiation;    In-control;    Low-intensity electromagnetic fields;    Proliferation activity;    Radiation-induced;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/487/1/012018/pdf
DOI  :  10.1088/1757-899X/487/1/012018

来源: IOP

【 摘 要 】

We have shown that γ-irradiation at dose of 10 Gy and low-intensity electromagnetic fields (EMF, 900 MHz, 100 μW/cm2, 180 min) significantly compromised cell proliferation of planarian S. mediterranea regenerating after decapitation. Using flow cytometry we have shown that 24 hours after exposure to γ-rays and EMF the index of proliferation established as the total amount of cells at S and G2/M phases was 2.8 and 1.8 lower than that in controls respectively. Our data therefore provide the first experimental evidence for the effects of medium-dose γ-irradiation on regeneration in planaria which is attributed to radiation-induced compromised proliferation activity.