Recent surveys show that mobile apps are more popular than Web apps. Apple’s iTunes Store, now has about800,000 apps and reported to have about 40 billion downloads. Android apps, although fewer, is available to themost number of smartphones today. About 40,000 apps are medical or health related. We developed a PubMed4Hhmobile app for iPhone/iPad users to search MEDLINE/PubMed with same features as our Webbased search tools,in use since 2002. Fiveyear (20082012) server data for PubMed4Hh and Web app were analyzed. Searches usingthe mobile app significantly increased compared to the same fiveyear time period. Monthbymonth comparisonshowed a 3 to 5fold increase in queries. The sixmonth total accesses comparison increased 280% from theprevious fouryear average. A review of 500 randomly selected queries revealed that the majority of queries were