Building Mouse Phenotype Ontologies

Pacific Symposium on Biocomputing 2004

GV Gkoutos ; ECJ Green ; AM Mallon ; JM Hancock ; D Davidson

PID  :  13932

来源: CEUR

【 摘 要 】

The structured description of mutant phenotypespresentsamajorconceptualandpractical problem. A general model for generating mouse phenotype ontologies that involvescombing avarietyofdifferentontologies tobetterlinkanddescribephenotypesispresented.This model isbasedon thePhenotypeandTraitOntologyschema proposal and incorporates practicallimitations and designing solutions in an attempt to modelatestbedforthefirst phenotypeontologyconstructedinthismanner,namelythemousebehaviorphenotype ontology.We proposetheapplicationofsuch amodelcouldprovidecuratorswitha powerfulmechanismofannotation,miningandknowledgerepresentationaswellas achieving some level of free text disassociation.