COMPUTATIONAL CHALLENGES IN COMPARATIVE GENOMICS: INTRODUCTION TO THE SESSION

Pacific Symposium on Biocomputing 2009

B.M.E. MORET ; W. MILLER ; P.A. PEVZENR ; D. SANKOFF

Others  :  http://psb.stanford.edu/psb-online/proceedings/psb09/intro-compgen.pdf
PID  :  19887

来源: CEUR

【 摘 要 】

Comparative methods have long been a mainstay of biology, particularly evolutionary biology; they are also at the core of medical research based on animal models of human physiology. They find their most challenging and most fitting application, however, in the study of whole genomes, as they are the main tools through which we can make sense of the billions of base-pairs forming the sequence of animal and other genomes. Comparing whole genomes, which is necessarily done through computational methods due to the size of the genomes, has given rise to the research area known as comparative genomics.