开放图书详细信息
| Drug-Acceptor Interactions - Modeling theoretical tools to test and evaluate experimental equilibrium effects | ||
| Niels Bindslev | ||
| Publisher: Co-Action Publishing | ||
| Subject:医学（综合） | ||
【 摘 要 】
Drug-Acceptor Interactions: Modeling theoretical tools to test and evaluate experimental equilibrium effects suggests novel theoretical tools to test and evaluate drug interactions seen with combinatorial drug therapy. The book provides an in-depth, yet controversial, exploration of existing tools for analysis of dose-response studies at equilibrium or steady state. The book is recommended reading for post-graduate students and researchers engaged in the study of systems biology, networks, and the pharmacodynamics of natural or industrial drugs, as well as for medical clinicians interested in drug application and combinatorial drug therapy. Even people without mathematical skills will be able to follow the pros and cons of reaction schemes and their related distribution equations. Chapter 9 is a hands-on guide for software to plot, fit and analyze ones own data.【 授权许可】
CC BY-NC
【 预 览 】
| Files | Size | Format | View |
|---|---|---|---|
| Acknowledgements.pdf | 24KB |  download |
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| Biological regulation and allostery.pdf | 107KB | download |
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| Chapter 10_ Hill in hell.pdf | 505KB | download |
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| Chapter 11_ The Schild against other theories.pdf | 464KB | download |
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| Chapter 12_ Ties between synergy and two-state models.pdf | 2783KB | download |
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| Chapter 13_ Strategies of biological regulation.pdf | 1011KB | download |
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| Chapter 14_ On allostery and co-operativity.pdf | 938KB | download |
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| Chapter 15_ Allostery and development of its models.pdf | 1200KB | download |
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| Chapter 1_ Simple agonism.pdf | 1508KB | download |
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| Chapter 2_ Simple ant-agonism - Simple intervention.pdf | 970KB | download |
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| Chapter 3_ Auto-inhibition and - auto-intervention in one-state models.pdf | 1303KB | download |
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| Chapter 4_ Means of obtaining ant-agonist constants. Preliminary points of a personal view.pdf | 349KB | download |
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| Chapter 5_ Complex agonism.pdf | 581KB | download |
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| Chapter 6_ Multi-step reaction schemes. Extending the two-step mechanism of del Castillo .pdf | 1119KB | download |
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| Chapter 7_ Cubic reaction schemes. ATSM and HOTSM.pdf | 4201KB | download |
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| Chapter 8_ Choosing and formulating relevant schemes.pdf | 441KB | download |
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| Chapter 9_ Plots, fits, and data interpretation.pdf | 3904KB | download |
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| Contents_Index.pdf | 84KB | download |
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| Drug-Acceptor Interactions-Modeling theoretical tools to test and evaluate experimental equilibrium effects.gif | 4KB | Image | download |
| One-state models - Simple agonism and ant-agonism.pdf | 122KB | download |
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| Preface.pdf | 38KB | download |
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| Test of tools for data analysis.pdf | 97KB | download |
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| Two-state models - Complex agonism and modulation.pdf | 75KB | download |
【 图 表 】
Drug-Acceptor Interactions-Modeling theoretical tools to test and evaluate experimental equilibrium effects.gif
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